Staff Software Engineer, RCM at Natera

POSITION SUMMARY: Natera is seeking a high-caliber Staff Software Engineer to revolutionize our Revenue Cycle Management (RCM) through cutting-edge agentic workflows and production-grade AI services. You will bridge the gap between advanced Large Language Models (LLMs) and the complex world of medical billing, healthcare compliance, and financial forecasting. This isn't just about "using an API." You will be architecting autonomous agents that read EOBs, navigate payer rules, and automate complex billing workflows—all while maintaining the rigorous security standards required in healthcare. PRIMARY RESPONSIBILITIES: • Systems Architecture: Design and deploy production-grade FastAPI services that wrap LLM calls, maintain stateful agent loops, and expose secure REST/GraphQL endpoints. • Agentic Workflows: Build and orchestrate intelligent agents capable of handling unstructured documents (EOBs, medical records) using vision-augmented NLP and multimodal LLMs. • Advanced RAG: Develop agentic RAG pipelines (chunking, embeddings, vector search) to surface critical codes and payer-specific rules in real-time. • Cloud Operations: Containerize and operate the stack on AWS ECS/Fargate. Own the IaC pipelines to ensure seamless, high-frequency deployments (dev → staging → prod) multiple times a day. • Observability & Analytics: Instrument services with OpenTelemetry, Grafana, and Sentry. Create dashboards to forecast denial rates, claim risks, and turnaround times. • Product Evolution: Extend our React-based UI to allow human operators to launch agents, replay conversations, and inspect evaluation traces. • Security & Compliance: Ensure every feature is architected to meet HIPAA, SOC 2, and Natera’s internal security benchmarks. QUALIFICATIONS: Technical Core • Python Mastery: Expert-level Python developer with a focus on FastAPI for high-performance, asynchronous services. • AI/LLM Stack: Deep experience with LLM orchestration (LangGraph, CrewAI, or similar) and building agentic workflows. • Tools of the Trade: Proficient in AI-augmented development using Claude Code, Gemini, and Cursor to accelerate delivery. • AWS Infrastructure: Solid experience with AWS (ECS/Fargate, Lambda, S3) and CI/CD best practices. Domain Expertise • Healthcare/RCM: Direct experience in Revenue Cycle Management, medical billing, or healthcare tech. You should understand the nuances of claims, denials, and payer-provider interactions. • Data Handling: Experience processing unstructured healthcare data and a solid grasp of multimodal AI (text + vision). Soft Skills • Collaborative Mindset: Ability to translate complex requirements from billing, compliance, and finance experts into resilient backend code. • Ownership: A "production-first" mentality—you don't just write code; you operate and monitor it. NICE TO HAVE: • Experience designing, configuring, and implementing external applications and integrations with a LabVantage LIMS application • Experience designing, configuring, and implementing infrastructure and software used by the LabVantage LIMS application • Experience in configuration and customization of commercial off-the-shelf product LIMS system to support order to result workflows • Experience performing upgrades of a LabVantage LIMS system • Experience with front-end web programming, preferably with modern JavaScript frameworks (react, angular, etc.) • Healthcare IT experience KNOWLEDGE, SKILLS, AND ABILITIES: • Object Oriented Programming • Python, FastAPI • Typescript • Relational Database and SQL Programming, prefer Oracle • REST APIs and other Web service backend technologies • CI / CD • Quality Assurance Mindset; Nice to have: familiarity with regulated environments The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.Remote USA$167,300—$209,100 USDOUR OPPORTUNITY Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives. The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management. WHAT WE OFFER Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program! For more information, visit www.natera.com. Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide. All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws. If you are based in California, we encourage you to read this important information for California residents. Link: [Upgrade to PRO to see link] Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes. For more information: - BBB announcement on job scams - FBI Cyber Crime resource page