Location: This position may be performed remotely, but requires the flexibility and willingness to travel as needed.
The Opportunity
The Tier II IT Support Specialist is a key player in delivering seamless technology experiences across Praxis. Youโll serve as the primary escalation point for complex technical issues, partnering closely with our internal IT support, development, and leadership teams to ensure smooth operations for our 260โ400 users.
From managing identity and access to administering collaboration platforms and overseeing IT assets, this role is essential to sustaining and scaling our tech infrastructure. This is a hands-on, high-impact position for someone who thrives on solving problems, documenting what works, and improving how we support our mission.
Primary Responsibilities
โข Serve as the go-to escalation point for Level 2 IT issues from our internal Helpdesk
โข Troubleshoot and resolve complex problems across Microsoft 365, collaboration tools, and endpoint devices
โข Support onboarding and offboarding workflows for employees, consultants, and contractors
โข Administer user access and authentication across Microsoft Entra ID and SaaS platforms
โข Manage SSO, MFA, password managers (1Password), certificates, and guest access
โข Handle admin consent requests and configure access for contractors and temporary roles
โข Administer permissions for SharePoint, DocuSign, Zoom AI, Atlassian, and other SaaS tools
โข Conduct periodic license reviews and audits across enterprise applications
โข Oversee laptop shipping, imaging, and inventory tracking in Jira
โข Manage conference room AV systems and recordings for company-wide meetings as needed to support vendors
โข Respond to security-related alerts and support access to secure systems and VPNs
โข Partner with vendors and internal teams to manage OEM support and renewals
โข Maintain IT knowledge base in Confluence and refine workflows
โข Proactively identify and implement improvements to enhance support quality and user experience
Qualifications and Key Success Factors
โข Bachelorโs degree in IT, Computer Science, or related fieldโor equivalent hands-on experience
โข 5+ years in Tier II support, service desk, or IT operations roles
โข Strong experience with Microsoft 365, Entra ID, N-Central and identity/access systems
โข Familiarity with Jira Service Management and Confluence is a plus
โข Comfortable supporting SaaS platforms and collaboration tools
โข Exceptional troubleshooting, documentation, and communication skills
โข A proactive, collaborative mindset with the ability to operate independently
โข Flexibility for occasional after-hours or on-call support
โข The physical and mental requirements of our roles include but are not limited to regular use of a computer, devices or other office equipment, clear communication, and occasional movement. You'll need comfort with screen work, basic hand coordination, and focus. Reasonable accommodations may be made to enable individuals with disabilities to perform these functions.
Annualized Base Salary$68,000โ$88,000 USDCompany Overview
Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders. Our core Values of Trust, Ownership, Curiosity and Results are foundational to every aspect of our business and are exemplified by each and every one of our team members.
Diversity, Equity & Inclusion
Guided by our core values, at Praxis Precision Medicines, Inc. we continue to DARE FOR MOREยฎ to advance, promote, and champion diversity, equity, and inclusion by encouraging individuals to bring their authentic selves and perspectives to work each day. We are an equal opportunity employer and committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws.
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