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Research Associate II - Antibody Validation at Flagshippioneeringinc
FlagshippioneeringincBoston, MA USA·8h ago
Mid LevelFull-time
Salary Range
$102,000 - $138,000 /year
This salary is estimated based on similar roles. The actual salary may vary.
About the Role
ProFound Therapeutics is seeking a Research Associate to join the Lab Operations Team and drive Antibody Validation. This role will play a critical hands-on role in the validation, characterization, quality control, and distribution of antibodies and protein reagents that support multiple internal scientific teams and external collaborations.
Key Responsibilities
- →Perform routine histology techniques including paraffin sectioning, standard histological stains, and immunohistochemistry (IHC), including novel antibody optimization.
- →Validate and characterize novel antibodies and proteins using established and emerging assay approaches.
- →Perform SDS-PAGE, Western blotting, and related protein analysis techniques to assess antibody specificity, sensitivity, and performance.
- →Execute antibody and protein quality control (QC) workflows to ensure consistency and reliability of internal reagents.
- →Maintain mammalian tissue culture to support antibody validation and functional testing.
- →Manage internal antibody and protein reagent inventories, including receiving, labeling, storage, and tracking.
- →Maintain accurate sample inventory and metadata in Benchling or related laboratory information systems.
- →Coordinate domestic and international shipments of biological samples in compliance with institutional and regulatory requirements.
- →Distribute samples to internal end users upon request, ensuring proper documentation and chain-of-custody.
- →Document experimental procedures, results, and QC outcomes in electronic laboratory notebooks.
- →Contribute to continuous improvement of Antibody Validation Core workflows and best practices.
Requirements
- ✓BS in Biology, Biochemistry, Molecular Biology, Immunology, or a related discipline with ~3+ years of relevant laboratory experience; MS with fewer years of experience will be considered.
- ✓Hands-on experience with SDS-PAGE, Western blotting, tissue culture, and basic protein biochemistry.
- ✓Direct experience with histology techniques, including H&E staining and immunohistochemistry (IHC), required.
- ✓Experience with antibody or protein validation and QC workflows.
- ✓Familiarity with laboratory inventory and sample tracking systems (e.g., Benchling or similar platforms).
- ✓Experience coordinating domestic and/or international biological shipments is a plus.
- ✓Strong organizational skills, attention to detail, and commitment to data integrity and reproducibility.
- ✓Excellent written and verbal communication skills.
