Bioinformatics Staff Data Scientist # 4768 at Grailbio

Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care. We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges. GRAIL is headquartered in the bay area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies. For more information, please visit grail.com Responsibilities: • Analyze complex high-dimensional datasets related to multi-cancer early detection test results from Grail’s commercial platform in order to identify empirical trends and then communicate findings across teams. • Integrate cancer biology, DNA methylation, genomics, epidemiology, and statistics to generate predictive models of expected test performance and identify potential deviations. • Participate in cross-functional interactions with interdisciplinary teams including machine learning, software engineering, clinical, laboratory operations, research, and product development. • Create and communicate rigorous scientific analyses. Required Qualifications: • Ph.D. in Bioinformatics, Data Science, Computational Biology, Physics, Bioengineering, Cancer Genomics, Statistics, Biochemistry or a related field with 5+ years of relevant experience • Proven track record in working with large-scale omics datasets in R (preferred) or Python. • Experience with NGS data processing, statistical modeling, and machine learning frameworks and their application to derive technical and biological insights in a clinical setting • Excellent communication, collaboration, and problem-solving skills; ability to work independently and effectively across interdisciplinary environments. • Demonstrated ability to perform rigorous and detail-oriented work. Preferred Qualifications: • Knowledge of cancer epigenetics, cancer biology, tumor genetics, and molecular mechanisms of oncogenesis • Experience with traditional ML and modern AI techniques • Track record of scientific contributions (e.g., publications, tools, datasets, patents, or conference presentations) • Proficiency in Python or R, with experience in modern data science workflows (Linux, Git, reproducible pipelines, etc…) • Interest in translating research innovations into production-ready systems This role may be eligible for other forms of compensation, including an annual bonus and/or incentives, subject to the terms of the applicable plans and Company discretion. This range reflects a good-faith estimate of the range that the Company reasonably expects to pay for the position upon hire; the actual compensation offered may vary depending on factors such as the candidate’s qualifications. Employees in this role are also eligible for GRAIL’s comprehensive and competitive benefits package, offered in accordance with our applicable plans and policies. This package currently includes flexible time-off or vacation; a 401(k) retirement plan with employer match; medical, dental, and vision coverage; and carefully selected mindfulness programs. GRAIL is an equal employment opportunity employer, and we are committed to building a workplace where every individual can thrive, contribute, and grow. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, gender, gender identity, sexual orientation, age, disability, status as a protected veteran, , or any other class or characteristic protected by applicable federal, state, and local laws. Additionally, GRAIL will consider for employment qualified applicants with arrest and conviction records in a manner consistent with applicable law and provide reasonable accommodations to qualified individuals with disabilities. Please contact us at [Upgrade to PRO to see contact] if you require an accommodation to apply for an open position. GRAIL maintains a drug-free workplace. We welcome job-seekers from all backgrounds to join us!