Jobs → Engineering → Cheminformatics amp; Python Solutions Developer

About the Role Pfizer Research amp; Development is seeking a skilled Cheminformatics amp; Python Solutions Developer to support molecular research, chemistry data management, and scientific digital transformation initiatives. Key Responsibilities • Curate, validate, standardize, and maintain chemical structure data • Perform structure normalization, salt and solvent handling, valence checks, charge normalization, tautomer treatment, stereochemistry review, and duplicate identification • Develop Python-based applications, APIs, libraries, and automated workflows for scientific data processing • Build scalable pipelines for chemical structure ingestion, transformation, validation, standardization, and export • Use cheminformatics toolkits such as RDKit, ChemAxon, or equivalent technologies • Develop substructure and similarity searches, scaffold analysis, descriptor calculations, compound clustering, and molecular property computation • Integrate chemistry platforms, scientific databases, enterprise systems, and cloud services through APIs • Support data preparation and feature engineering for predictive modeling, molecular design, and AI/ML research • Collaborate with medicinal chemists, computational scientists, informaticians, data scientists, and software engineering teams Requirements • Strong Python development and workflow automation experience • Cheminformatics and chemical structure processing • Hands-on experience with RDKit, ChemAxon, or equivalent tools • Chemical data curation, structure validation, normalization, and compound registration • Scientific data pipelines, API development, and system integration • Molecular similarity analysis, substructure searching, molecular descriptors, and property calculations • Code testing, documentation, code reviews, and maintainable software development practices • Ability to collaborate with chemistry and research teams to deliver scientifically meaningful solutions